Wednesday, January 14, 2009

Hypertension or obesity so that the biological effects of insulin in patients with high blood pressure is being undermined. At that time people have..

What is Hyperinsulinemia
Hypertension or obesity so that the biological effects of insulin in patients with high blood pressure is being undermined. At that time people have the body to insulin resistance, and in order to maintain a more normal blood glucose levels, their body self-regulation mechanisms to pancreatic β-cell secretion than normal times or even ten times more insulin to lower blood sugar, and this has given rise the hyperinsulinemia. Hyperinsulinemia is defined as fasting insulin ≥ 85 pmol / L.
Hyperinsulinemia is coronary heart disease, hypertension, hyperlipidemia, type 2 diabetes, obesity, stroke and so on the basis of a common pathogenesis.

Hyperinsulinemia treatment
To strengthen the sports exercise: to increase physical activity on insulin sensitivity of organizations to reduce weight, improve metabolism, reduce the insulin resistance, so that hyperinsulinemia mitigation, reducing cardiovascular complications.

To improve the diet: Whether in China or in the West, people's diet structure to high-calorie, high-fat-based. And excessive calorie intake over consumption, the result of body fat storage trigger obesity. Therefore, the diet should be diversified in order to maintain nutritional balance, avoid excess nutrients.

Hypertension and the relationship between hyperinsulinemia
In recent years, hyperinsulinemia and hypertension cause for concern. Observed that the hypertensive patients fasting insulin levels were significantly higher than normal, there is insulin resistance, and impaired glucose tolerance to reduce the incidence of hypertension were significantly higher than normal, hyperinsulinemia are also often accompanied by hypertriglyceridemia and low high-density lipoprotein hyperlipidemia, the performance was particularly prevalent in the obese.

Animal studies have also found that insulin resistance exists SHR. Hyperinsulinemia may be the cells by activating Na +-K + ATP enzyme to intracellular Na + concentration increased, the body of sodium retention, reduce Ca2 +-ATP activity to increase intracellular calcium concentrations to increase in vascular resistance, and increased sympathetic activity lead to hypertension. However, not all hyperinsulinemia have a high blood pressure, and vice versa, the relationship between the two still continue to study.

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